A rare mutation has occurred within the vampire community – The Reaper. A vampire so consumed with an insatiable bloodlust that they prey on vampires as well as humans, transforming victims who are unlucky enough to survive into Reapers themselves. Blade is asked by the Vampire Nation for his help in preventing a nightmare plague that would wipe out both humans and vampires.
Wesley Snipes, Kris Kristofferson, Ron Perlman, Leonor Varela, Norman Reedus, Thomas Kretschmann, Luke Goss, Matt Schulze, Danny John-Jules, Donnie Yen, Karel Roden, Marit Velle Kile, Tony Curran, Daz Crawford, Santiago Segura, Samuel Le, Marek Vašut, Pete Lee-Wilson, Paul Kasey, Andrea Miltner, Ladislav Beran, Jiří Maria Sieber, Bridge Markland, Jamie Wilson, Stuart Luis, Ladislav Mohyla, Jan Malík, Jan Révai, Mário Wild, Tomás Böhm, Zdenek Bubák, Jan Loukota, Jan Bursa, Petr Krusalnicky, Jaroslav Misek, Karel Vávrovec, Jaroslav Peterka, Milos Kulhavy, Ivan Mares, Lennox Brown, André Hyde-Braithwaite, Pavel Cajzl, Olga Lounová, Stephen R. Peluso, John Paul Salvitti, Rey-Phillip Santos, Kenji Tanigaki, Michael F. Woods
Guillermo del Toro
David S. Goyer